Paper vs. eCRF

There are specific advantages and disadvantages for each medium, that can be used for a study

Advantages Disadvantages
Paper Easy data entry
No training needed
No computer expertise needed
Low expenditure for programming
Marketing effect due to presence at the doctor
Printing & postage costs
Delivery time
Implausibilities lead to paper queries with additional running time
Electronic Directly checked for plausibility
Less queries needed
Study progress known
Latest data available
No training due to intuitive user guidance
Higher expenditure for programming
Selects doctors by digitization status
Hybride All advantages of paper studies
All advantages of electronic studies
Identical layout paper & eCRF
No selection of doctors
High overall expenditure